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Doyle Lab

Current Lab Members and Projects

  •  Jared Bithell (2019): Improving TAL Effector binding site prediction for disease resistance QTLs in rice
  • Craig Bramhall (2019): Using phage therapy with Propionibacterium acnes phages to treat acne
  • Hailie Crull (2019): Isolation and use of bacteriophage specific to Propionibacterium acnes to treat acne
  • Nick Iwata (2019): Automation of calibration grid detection on ninhydrin paper root blots
  • Jade Prochaska (2019): Isolation of bacteriophage infecting Pseudomonas syringe pv. tomato and their effect on bacterial infections in the host plant Nicotiana benthamiana 
  • Kaitlyn Mahnke (Summer 2018): Use of SUP-TALs to suppress gene expression in prokaryotic organisms

Current Research Collaborations and Other Projects

DIVAS Project

QTL Crop Editing

Center for Root and Rhizobiome Innovation (CRRI)



Doane University Senior Research Projects From Other Years

  • Blake Kostal (2018) and Dylan Mayfield (2018): Use of SUP-TALs to suppress eGFP expression in Pseudomonas aeruginosa PA14
  • Michael Shavlik (2018)*: Epigenetic Modifications in Arabidopsis thaliana may contribute to plasticity of root gravitropic response patterns
  • Zackry Stevenson (2018): Isolation of a bacteriophage specific to Propionibacterium acnes from human skin
  • Jordan Zonner (2018): Image based detection of induced hypersensitive response in Nicotiana benthamiana
  • Dalton Bichlmeier (2017)*: Naturally occurring Xanthomonas oryzae TALEs have the same number of predicted sites in both Xanthomonas oryzae pathovars
  • Riley Jones (2017, co-mentored with Tessa Durham Brooks)*:  Defense related gene expression in Response to Biofilm Formation on the Roots of Arabidopsis thaliana*
  • Erin Keetle (2017): Incorporation of new experimental data improves prediction of TAL effector-targets in rice disease
  • Katelyn O’Brien (2016): Clustering phages by tetra-nucleotide percentages may form groupings better displaying host range for mycobacteriophage
  • Logan Berggren (2015): Measuring amounts of P. aeruginosa biofilm on short-wear and continuous-wear contact lenses after normal periods of growth
  • Nick Chapek (2015): Genes involved in biofilm formation are regulated by a specific factor or set of factors
  • Tanner Clark (2015) and Cole Morgan (2015): Gene expression changes in biofilm development and quorum sensing inhibition
  • Renee Mandock (2015): Comparison of the genomes of known mycobacteriophages to novel mycobacteriophages assigns the novel mycobacteriophages to Cluster A

* indicates the project also met the requirements for the Computational Science minor


Other Research Students and Projects

  • Gage Herron (Summer 2018): Exploring alternative hosts for bacteriophage discovery and isolation
  • Truc Doan, Adreanna Ernest, and Danny Tran (Summer 2017): A low-cost imaging method for the temporal and spatial colorimetric detection of free amines on maize root surfaces
  • Erin Lawyer, Allison Morrill, and Aubrey Schatz (Summer 2017): Development of custom Python code for image-based quantification and analysis of hypersensitive response in Oryza sativa and Nicotiana benthamiana
  • Kaycee Bartels, Adela Chen, Nadezdha Hughes, and Jordan Zonner (Summer 2016). Using custom Python code to explore the evolution of Xanthomonas TAL effector proteins for plant disease susceptibility.
  • Dalton Bichlmeier, Blake Kostal, and Michael Shavlik (2015-2016). Comparison of TAL effector EBE variation across 3,000 sequenced rice genomes.
  • McKenna Ahrens and Dalton Bichlmeier (Summer 2015): Comparison of TAL effector binding site variation across 3000 rice genomes
  • McKenna Ahrens and Kendall Kramer (March-May 2015): Identification of reverse-oriented TAL effector bindings sites in the rice genome sequence
  • Nicolas Booher (Iowa State University, 2012), Development of a TAL effector-target prediction web interface. Project led to a publication with the student as a co-author
  • Angela Chang (NSF REU project at Iowa State University, 2011). The effect of amino acid substitutions in the cryptic -1 st repeat on TAL effector binding specificity for base 0